COVID-19 Response — Due to the evolving COVID-19 outbreak, particularly in Washington state, please be aware that our staffing and operations may be impacted for the next several weeks. We value your business and will respond to inquiries and issues as best we can and we appreciate your patience while we work through this ever changing situation. Updates

Alliance's LES Harm Reduction Center

The Alliance for Positive Change

The Alliance for Positive Change helps New Yorkers living with HIV/AIDS and other chronic illnesses access medical care, manage and overcome addiction, escape homelessness, get back to work, and find a sense of community. At the Alliance, we believe everyone deserves the chance to feel better, live better, and do better.

  • Case Management/Coordinated Care
  • Community Trainings/Education
  • Drop-in center
  • Hepatitis testing/Education
  • HIV testing/Education
  • MAT Education/Referrals
  • Naloxone Distribution/Overdose Ed.
  • Syringe Services
  • Wound Care Services

25 Allen
New York, NY 10002 US


25 Allen Street (Between Hester and Canal Street)

Mon-Fri: 10:00am to 8:00pm

Sat: 10:00am to 5:00pm

Washington Street (Between Gansevoort & West 13th Street)

Friday (Winter Hours) 6:00pm to 9:30pm

Friday (Summer Hours) 7:00pm to 11:00pm

Roving Team in the general areas of east 20th street to the North, 5th Avenue and Bowery to the the West and the FDR Drive to the East and South, "Walkabout" winter hours are in effect 11/16-3/15 and summer hours are in effect 3/16-11/15 please call or email for questions:

Mon-Fri: 5:00pm to 8:00pm

Wed: 8:00pm to 11:00pm

Thu: 11:00am to 2:00pm

Sat: 11:00am 2:00pm


(212) 226-6333
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